For the preventive treatment of migraine in adults.

For the preventive treatment of migraine in adults.

Patient Information Información del Paciente
Prescribing Information Información de Prescripción
Nurse helping VYEPTI® patient with IV bag.

Why IV Treatment

Migraine prevention
delivered differently

Actor portrayal

Discover intravenous (IV) infusion

VYEPTI was purposefully designed as an IV infusion to start working fast and keep working through month 3 after each infusion.

Just four 30-minute IV infusions a year (every 3 months) given by a healthcare provider.

100% of the medication is delivered into your bloodstream, so it can get right to work.

The VYEPTI difference

Take a closer look at what you can expect during and after your VYEPTI IV infusion experience, including how quickly you can get back to your day. And that's not all—learn about the results with VYEPTI, such as how fast the medication can start working and how long it can last.

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0:08 VYEPTI is different.​

0:13 VYEPTI is the first and only FDA-approved intravenous (IV) infusion for the preventive treatment of migraine.​

0:20 It's delivered to your body in a different way...

0:22 …as a 30-minute IV infusion given just 4 times a year.

0:28 VYEPTI is designed to work fast. During each 30-minute infusion, 100% of the medication goes directly to your bloodstream and begins circulating.

0:35 And just one infusion can provide 23 fewer migraine days over 3 months.

0:40 Now let’s take a closer look at how VYEPTI works and what you can expect during and after treatment.

0:47 Inside the body, there’s a protein called calcitonin gene-related peptide, or CGRP. CGRP attaches to and activates specific receptors, which may play a role in migraine.

1:02 VYEPTI blocks CGRP and prevents it from attaching to and activating the receptors.

1:07 So what’s the infusion experience like? The infusion location can be flexible. Depending on your insurance, you can receive your VYEPTI treatment at an infusion center, at your doctor’s office, or even at home.

1:22 Once you’ve gotten comfortable in your infusion chair, you’re in the hands of healthcare professionals—just sit back and relax for the next 30 minutes.

1:32 When your infusion is complete, there's no downtime. You can go about your day and get back to your normal activities.

1:40 Just be sure to schedule your next infusion before you wrap up, and space treatments no more than 3 months apart.

1:45 Now what kind of results might you experience after treatment?

1:54 With VYEPTI, more people had migraine-free days during the first week after treatment—some as soon as Day 1.

2:00 And the results are lasting. VYEPTI keeps working through month 3 after each infusion. That’s why you only get an IV infusion treatment 4 times a year. Common side effects on VYEPTI are allergic reactions, stuffy nose, and scratchy throat.

2:15 And if you have any questions between treatments, no problem—the VYEPTI nurse support program lets you talk one-on-one with a registered nurse.

2:25 Ask your migraine specialist if VYEPTI could make a difference for you.

2:28 And that's not all. Stick around for the full important safety information.

VYEPTI dosing

VYEPTI is a preventive treatment for migraine that’s delivered differently. Check out how often these preventive migraine treatments are given.

This is not a comparison of how well each treatment works or how safe they may be.

IV infusion
VYEPTI® (eptinezumab-jjmr)
4x a year
One 30-minute infusion administered by a healthcare provider 4x a year
One 30-minute infusion administered by a healthcare provider 4x a year
Injection
Aimovig® (erenumab-aooe)
12x a year
One self-injection 1x a month
One self-injection 1x a month
AJOVY® (fremanezumab-vfrm)
12x or 4x a year
One self-injection 1x a month or 3 self-injections, 4x a year
One self-injection 1x a month or 3 self-injections, 4x a year
BOTOX® (onabotulinumtoxinA)
4x a year
31 injections at each treatment visit, 4x a year
31 injections at each treatment visit, 4x a year
Emgality® (galcanezumab-gnlm)
12x a year
One self-injection 1x a month (after initial loading dose*)
One self-injection 1x a month (after initial loading dose*)
Pill
Nurtec® ODT (rimegepant)
182x a year
One pill every other day
One pill every other day
QULIPTA® (atogepant)
365x a year
One pill 1x a day
One pill 1x a day

*The first dose is a loading dose and may be given as 1 or 2 injections. The above is not a complete list of preventive treatments of migraine in adults. The comparison pertains only to differences in dosing and administration and should not be considered a comparison of efficacy or safety. Trademarks are the property of their respective owners. Please see each product's full Prescribing Information for additional information, including indication, dosing, and safety.

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“Before my first infusion, I was a little bit nervous. But for me, it was easy, and the 30 minutes went by really quickly.”

Lealani, VYEPTI patient

The infusion will take about 30 minutes, but your total appointment time may vary.
Lealani was compensated for her time.

Lealani, VYEPTI® patient ambassador.

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Take a look

VYEPTI could help you have more migraine-free days

Proven migraine prevention in 2 clinical studies. This you’ll want to check out.

Check the results

Start the conversation

Ready to talk with your doctor about VYEPTI?

Before your next appointment, create your own Doctor Discussion Guide with personalized responses specific to your concerns and experience with migraine.

Create your guide
IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

IMPORTANT SAFETY INFORMATION

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.

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The product information provided in this site is intended only for residents of the US. The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider.