For the preventive treatment of migraine in adults.
For the preventive treatment of migraine in adults.
For the preventive treatment of migraine in adults.
For the preventive treatment of migraine in adults.
Find answers to your questions about VYEPTI, how it works, side effects, support, and more.
VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults. It is the 1st and only FDA-approved intravenous (IV) infusion for the preventive treatment of migraine. VYEPTI is given as a 30-minute IV infusion 4 times a year (every 3 months).
VYEPTI is an aCGRP, a type of medication designed for the preventive treatment of migraine. aCGRPs are recommended by the American Headache Society (AHS) to be one of the first types of preventive treatment prescribed to people with migraine.
The relationship between your body’s response to the medication and how VYEPTI prevents migraine is not known.
An intravenous, or IV, infusion is designed to deliver medicine directly into the bloodstream, so the medication can circulate throughout the body during infusion and get right to work.
By contrast, a subcutaneous injection is given under the skin, and the delivery of medication to the bloodstream is slower.
VYEPTI is a powerful preventive treatment for migraine that’s proven to reduce monthly migraine days and last for 3 months after treatment. More people treated with VYEPTI had fewer monthly migraine days through month 3 compared with placebo.
The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions. These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or does not go away. Please read the Important Safety Information below and read the VYEPTI Patient Information to understand all the possible side effects.
If you've been working hard to manage migraine and are wondering if VYEPTI could be right for you, talk with your healthcare provider.
There are a few things you can do to help prepare for your VYEPTI treatment, including:
Before: Enroll in VYEPTI GO to talk with a registered nurse for helpful information, such as resources and tips to help you get started. Confirm where you're going to get your infusion and drink plenty of water on infusion day.
During: Relax and ask any questions you may have.
After: Make your next infusion appointment in 3 months and get back to your daily routine.
Use the VYEPTI infusion locator and work with your doctor and insurance to decide on a location that's best for you: depending on your insurance, you may be able to receive your infusion at your doctor's office, your home, a hospital outpatient clinic, or an infusion center. You've got this.
If you have been prescribed VYEPTI and have questions about treatment, you can talk with a registered nurse by enrolling in the VYEPTI GO program.
If you still have questions about finding an infusion location, call 833-4-VYEPTI (833-489-3784), option 1 for support.
Depending on your insurance, you can receive a VYEPTI infusion treatment at an infusion center, at your doctor's office, a hospital outpatient clinic, or in the convenience of your home. Check with your healthcare provider to find out if their office provides VYEPTI infusions, or ask your insurance provider if you qualify to receive VYEPTI from a registered nurse in the comfort of your home. Use the VYEPTI infusion locator to find an option that could work for you.
Some people in the VYEPTI clinical studies had migraine attacks on the day they received treatment. While there are no limitations of use with VYEPTI, if you have a migraine attack on the day of your scheduled VYEPTI infusion, talk with your healthcare provider.
Before a person is given VYEPTI, they should tell their healthcare provider if they are pregnant or plan to become pregnant, or if they are breastfeeding or planning to breastfeed. Read the VYEPTI Important Safety Information.
Notify your healthcare provider immediately if you become pregnant while taking VYEPTI. Read the VYEPTI Important Safety Information.
If you are pregnant, consider signing up for the VYEPTI pregnancy registry to help us learn more about VYEPTI and pregnancy (www.vyeptipregnancyregistry.lundbeck.com).
Although VYEPTI can be prescribed by any authorized healthcare provider, they may refer you to a migraine/headache specialist or a neurologist.
There are a couple of support options for people who are prescribed VYEPTI. With VYEPTI GO, you'll have access to a registered nurse who can answer questions about VYEPTI and more. If you're looking into details of your healthcare insurance coverage or finding treatment locations, talk to your healthcare provider about enrolling you in VYEPTI CONNECT for informational support along your treatment journey.
The VYEPTI copay assistance program helps eligible people with commercial insurance pay as little as $0 every 3 months for their VYEPTI infusion. Offer includes 100 mg and 300 mg doses. Eligibility criteria and program maximums apply. This offer is NOT available for people enrolled in Medicare, Medicaid, or any other government healthcare program. Please see the full Terms and Conditions.
Offer includes up to $200 in administration out-of-pocket fees per VYEPTI treatment. Additionally, the amount you pay may differ depending on the healthcare provider administering your infusion. Terms and conditions apply.
Check your eligibility for the VYEPTI copay assistance program and enroll yourself, or ask your healthcare provider or infusion provider to enroll you.
If VYEPTI was ordered through a specialty pharmacy, you will need to complete these few steps to ensure that your prescription is filled and shipped to your selected infusion location.
Migraine is more than just a bad headache; it’s a neurological disease that affects 39 million Americans. It is likely that you or someone you know suffers from migraine.
Symptoms can be different for everyone. Some people may have pain or discomfort, aphasia (trouble with speech), auras (including visual disturbance), be sensitive to light and sound, feel sick to their stomach, and/or vomit. For example, people with ocular migraine may experience vision loss and blind spots, while people with vestibular migraine may have their sense of balance affected.
The number of migraine attacks each month can vary. Some people have 15 or more migraine days in a month. This can really impact quality of life—more than 90% of people are unable to work or live their lives normally during a migraine attack.
Chronic migraine is characterized by 15 or more headache days per month, with at least 8 of those being migraine days.
Episodic migraine is characterized by 4 to 14 headache days per month, with at least 4 of those being migraine days.
In a large US survey, 17% of women and 6% of men reported having migraine symptoms. Women also tend to have longer migraine attacks, increased risk of their headaches coming back, more severe symptoms, and a longer recovery period.
One reason for the difference is that estrogen, a hormone typically found in higher levels in women, impacts brain activity. Differences in brain structure and genetic mutations are some other factors that make women more likely to get migraine attacks.
Calcitonin gene-related peptide, or CGRP, is a protein in the body that is believed to be a key cause of migraine. Changes in estrogen levels—like during a menstrual cycle, pregnancy, or in the transition to menopause—can affect CGRP activity and trigger migraine attacks. Hormonal medications, such as oral contraceptives, can also impact migraine. Be sure to tell your doctor about all the medications you take, including hormone therapy, and if you are pregnant or breastfeeding.
Many people with migraine notice certain signs or triggers that signal an upcoming attack. A trigger is a specific event that can set off a migraine, and these triggers vary from person to person. By identifying your migraine triggers, you can better prepare for and manage your migraine attacks. According to the Mayo Clinic, some common migraine triggers are:
Symptoms are different—they are something that a person feels or experiences during their condition. Like triggers, migraine symptoms can be different for everyone.
During the first phase, some patients may experience certain symptoms as early as 3 days before a migraine. This may allow patients to correctly predict migraine headache up to 12 hours before its onset.
Common migraine symptoms experienced during this phase are:
Migraine is a chronic disorder, and migraine prognosis is different for everyone. That’s something your doctor can discuss with you, along with a migraine treatment plan.
Each migraine attack can be different, too. There are four phases of a migraine attack—prodrome, aura, headache, and postdrome—but not everyone experiences all the four stages of a migraine attack.
Typically, a migraine attack can last for 1 to 2 days. The headache phase alone can last from four hours to three days, and in some cases, an attack with all four phases may last anywhere from about a day to about a week.
Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.
VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.
VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.
Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.
Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.
The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.
These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For more information, please see the Prescribing Information and Patient Information.
VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.
Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.
VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.
Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.
Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.
The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.
These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For more information, please see the Prescribing Information and Patient Information.
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