What to Expect During Treatment

Getting ready
for VYEPTI

What to keep in mind when choosing an infusion location

An intravenous (IV) infusion may be a new experience for you—but the flexibility of choosing a location can help you get started. Once your doctor has prescribed VYEPTI, work together with your insurance provider to set up the first appointment in a location most comfortable to you.

Through VYEPTI CONNECT®, program staff can work with your doctor and insurance provider to confirm if the selected infusion location(s) are covered by your plan. If your doctor sent a prescription to a specialty pharmacy, this brochure can help.

Depending on your insurance, you can choose from:

  • An infusion center
  • Home infusion
  • Infusion at your doctor’s office

Here’s what people have to say about this IV treatment

Based on a survey of 75 people enrolled in VYEPTI GO® as of November 2021:

  • 93% agreed that receiving treatment from a healthcare provider was reassuring
  • 95% agreed that scheduling the next infusion was easy
  • 96% agreed that the infusion experience was positive

Individual results may vary

Prepare for each step

Getting ready for your IV infusion

  • Drink plenty of water leading up to your appointment so that you are well hydrated
  • Wear comfortable clothing. Make sure long sleeves can be rolled up over your elbow
  • Bring an extra layer of clothing in case the infusion location is chilly

  • Have what you need and know where you’re going

  • As with most appointments with a healthcare provider, bring needed paperwork with you, such as a list of all medications you are taking
  • Have the address of the infusion location handy, as it may be different from where you go to see your healthcare provider

Given by a healthcare provider

  • A nurse or other healthcare provider will start your infusion and be available to answer any questions you may have
  • VYEPTI 100 mg is the recommended dose, but your healthcare provider may decide that you could benefit from a 300 mg dose

Infusion time

The infusion will take about 30 minutes, but your total appointment time may vary.


Sit back and relax

Use this time to read, check emails, connect on social media, share your experience, or just relax.

Make your next appointment

Schedule your next VYEPTI appointment in 3 months before you leave the infusion location


Return to your daily activities

Once your infusion is over, you can go about your day

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Here’s what people have to say about this IV treatment

Based on a survey of 75 people enrolled in VYEPTI GO® as of November 2021:

  • 93% agreed that receiving treatment from a healthcare provider was reassuring
  • 95% agreed that scheduling the next infusion was easy
  • 96% agreed that the infusion experience was positive

Individual results may vary

Select safety information

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

Meet Lealani, VYEPTI patient

Lealani shares her infusion experience with VYEPTI, and talks about being able to play music and feeling hopeful now that she has more migraine-free days.

Individual results may vary

Lealani, VYEPTI® patient infusion experience video.
Open transcript
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0:12 My name is Lealani, I'm a mother, I enjoy crafting and playing the violin, and I'm a Migraine Victor and this is my story.

0:24 I was 5 years old when I had my first migraine attack; they went undiagnosed until I was 18.

0:31 Migraine isn't just a headache; it's a full body experience–it affects everything.

0:37 For me, migraine are devastating physically. I get an aura.

0:45 For me, they’re bright neon colors, bright flashy lights and nauseating.

0:53 When I'm in a migraine attack, I will go to my room and I will close out all the lights, but it gets lonely being by yourself in the middle of a migraine attack.

1:06 It has caused me to lose jobs, it has caused me to not experience things with my family.

1:14 I almost missed my own wedding. There's not anything in my life that migraine hasn't touched.

1:22 Before VYEPTI, I tried everything from natural remedies to a multitude of prescriptions. Before VYEPTI, I could not write things on a calendar and expect to keep them there so I wrote things on sticky notes. I would have a migraine and have to cancel.

1:41 How I heard about VYEPTI getting approved is I watched some of the migraine message boards, and when I heard that VYEPTI did get approved, actually my children and I went out and we celebrated with dinner out.

2:11 Hi Lealani, so you’re here today to receive VYEPTI. As you know, this treatment will be given to you as an IV infusion, delivering the medication right into your bloodstream.

2:20 Great, I’m ready and excited to get this going.

2:23 Okay, let's get started. It's important to prepare for your infusion by making sure you are well hydrated, and if you are wearing sleeves, make sure they are loose enough to roll up above your elbows.

2:33 Side effects are possible. Allergic reactions such as rash, swelling of the face, lips, tongue, or throat, trouble breathing, hives, and redness in the face can occur. Common side effects are stuffy nose, scratchy throat, and allergic reactions.

2:50 If you start to have any symptoms during your infusion, including the ones I just mentioned, let me know right away.

3:08 Once the infusion starts, it will take about 30 minutes, so you can sit back, relax, you can use this time to read, or use your phone to check emails, or catch up on social media. Feel free to just take this time for yourself.

3:32 Looks good! We’re done.

3:34 That was fast, what do I need to do now?

3:36 Why don't you take a minute to get your things together and you can set up your next infusion appointment 3 months from now, then you're all set to go about your day.

3:47 Before my first infusion, I was a little bit nervous. But for me, it was easy and the 30 minutes went by really quickly.

3:59 It's fantastic to have a real person, like a nurse, get in contact with you and give you great tips about what to expect for your infusion date.

4:14 Since VYEPTI, I have the possibility of waking up without a migraine. And I know that I can do things. I know that I can open my curtains and let the sunshine in. Now, with VYEPTI, I can write things with a felt tip pen, I can play music.

4:38Now, I feel hopeful, triumphant.

4:44 My family has a saying, “Darn it do it” and now I can.

Select safety information

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Resources to help you navigate treatment

VYEPTI Connect™ logo.

VYEPTI CONNECT Brochure

VYEPTI CONNECT can provide you with patient support—from checking your insurance coverage for VYEPTI to locating infusion centers, we're in this with you.

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Specialty Pharmacy Brochure

If your healthcare provider sent your VYEPTI prescription to a specialty pharmacy, follow these 3 steps.

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Copay Assistance Flashcard

Learn how the VYEPTI CONNECT Copay Assistance Program might help you save on treatment.

You’ll want to know about this

Financial support is here

VYEPTI CONNECT may be able to help with savings, insurance information, infusion coordination, and more.

Have questions?

Talk with a nurse

VYEPTI GO® is a personalized treatment support program for people currently taking VYEPTI. The program staff can also provide information to anyone who is simply VYEPTI-curious.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.