Get ready to talk to your doctor about VYEPTI with help from these 2 tools

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Take the migraine quiz

How does migraine affect your daily life? Take this interactive quiz to see how migraine is affecting you and the impact it has on your ability to take part in everyday activities.

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Talk with your healthcare provider

Customize this Doctor Discussion Guide to choose the questions that are most important to you. 

Learn about VYEPTI and available support

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VYEPTI brochure

Learn about VYEPTI, including treatment benefits and what to expect from an IV treatment, side effects, and more.

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Copay assistance

Learn how the VYEPTI CONNECT Copay Assistance Program could help eligible, commercially insured patients with the cost of VYEPTI.

VYEPTI GO logo

VYEPTI GO flashcard

Get important information about VYEPTI GO, the personalized patient support program for people taking VYEPTI.

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VYEPTI home infusion

If your healthcare provider selected home infusion for your treatment, learn what to expect.

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Specialty pharmacy

If your healthcare provider sent your VYEPTI prescription to a specialty pharmacy, follow these 3 steps.

Connect with the migraine community

The migraine community is a strong and supportive group of people with advice, insights and experience to share about living with migraine. Here are a few ways to become a part of this community. 

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Real stories from real people

Hear real stories from real people who are living with migraine and who may also be receiving VYEPTI treatment. You can also share your own story and speak 1-on-1 with a Migraine Victors Program (MVP) Mentor.

LEARN ABOUT MVP

Explore some local and national migraine advocacy and community organizations 

American Migraine Foundation logo
American Migraine Foundation

American Migraine Foundation mobilizes the community for patient support and advocacy and supports impactful research that translates into advances for people with migraine and other disabling diseases that cause severe head pain.

The Association of Migraine Disorders logo
Association of Migraine Disorders

The Association of Migraine Disorders strives to expand the understanding of migraine and its true scope by supporting research, education, and awareness.

CHAMP logo
CHAMP

CHAMP improves the lives of people with migraine, cluster, and other headache diseases by aligning coalition members and empowering patient voices.

Chronic Migraine Awareness, Inc. logo
Chronic Migraine Awareness, Inc.

Chronic Migraine Awareness, Inc. is the voice of the chronic migraine community, offering support groups and teaching you how to advocate for yourself and others.

Miles for Migraine logo
Miles for Migraine

Miles for Migraine hosts Walk/Run/Relax events, education events, support groups, and volunteer groups. We support headache fellowship programs to increase research and foster advocacy for adults and children.

The National Headache Foundation logo
The National Headache Foundation

National Headache Foundation is the oldest and largest foundation for people living with migraine disease and headache disorders. NHF’s focus is education, advocacy, research, and furthering awareness of headache and migraine as legitimate neurobiological diseases.

The World Health Education Foundation logo
The World Health Education Foundation

World Health Education Foundation serves those who live with chronic illness and their caregivers. We specialize in migraine initiatives that help provide patients with affordable access to care, better education, and advocacy.

VYEPTI FAQs

Have questions? Find answers to a few frequently asked questions (FAQs) here.

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What is migraine?

Migraine is more than just a bad headache; it’s a neurological disease that affects over 39 million Americans. It’s likely that you or someone you know suffers from migraine.                               

Symptoms can be different for everyone. Some people may have throbbing head pain, be sensitive to light and sound, feel sick to their stomach, and/or vomit.

The number of migraine attacks each month can vary. Some people have 15 or more migraine days a month. This can really impact your quality of life—more than 90% of people are unable to work or live their lives normally during their migraine.

What is VYEPTI?   

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults. It is the first and only FDA-approved intravenous (IV) infusion treatment that’s proven to reduce monthly migraine days. VYEPTI is given as a 30-minute IV infusion 4 times a year (every 3 months).

What are the benefits of treatment with VYEPTI?  

VYEPTI is powerful migraine prevention that’s proven to reduce monthly migraine days from the very first treatment. More people treated with VYEPTI had fewer monthly migraine days through month 3 compared with placebo.

What are the most common side effects of VYEPTI?

The most common side effects of VYEPTI include stuffy nose, scratchy throat, and allergic reactions. These are not all the side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Please see Important Safety Information below and read the VYEPTI Patient Information.

Could VYEPTI be right for me?  

Talk with your healthcare provider to find out if treatment with VYEPTI may be right for you. If migraine is holding you back, preventive migraine treatment with VYEPTI could help. Here are 2 ways to help start the conversation:

What do I need to do to prepare for my 30-minute VYEPTI treatment?

There are a few things you can do to prepare for your VYEPTI treatment, including:

Before: Drink plenty of water, confirm where you're going to get your infusion, and enroll in VYEPTI GO.

During: Relax and ask any questions you may have.

After: Make your next infusion appointment in 3 months and get back to your daily routine.

What if I have a migraine attack on the day of my VYEPTI infusion?

Some people in the VYEPTI clinical studies had migraine on the day they received treatment. While there are no limitations of use with VYEPTI, if you have a migraine on the day of your scheduled VYEPTI infusion, talk with your healthcare provider.

Can VYEPTI be given to people who are pregnant or planning to become pregnant?

Before a person is given VYEPTI, they should tell their healthcare provider if they are pregnant or plan to become pregnant, or if they are breastfeeding or planning to breastfeed. Read the VYEPTI Important Safety Information.

Can my primary care provider prescribe VYEPTI, or will I need to be referred to a specialist? 

Although VYEPTI can be prescribed by any authorized healthcare provider, they may refer you to a migraine/headache specialist or a neurologist. 

Is there a patient support program for VYEPTI?

If you’re looking into details of your healthcare insurance coverage or coordinating treatment locations, VYEPTI CONNECT can provide you with informational support along your treatment journey. Through VYEPTI GO, you can speak with a registered nurse for personalized support. Learn more about how VYEPTI CONNECT and VYEPTI GO can help.

Interested in talking 1:1 with someone who can tell you about their personal migraine experiences, including taking VYEPTI? Connect with a mentor through the MVP Mentor Program.

Is there a way to save on the cost of VYEPTI?

The VYEPTI CONNECT Copay Assistance Program helps eligible people with commercial insurance pay as little as $5 every 3 months for VYEPTI and save up to $4000 every calendar year. Interested in enrolling? Check your eligibility.

Note: The program covers the cost of VYEPTI only. You may be responsible for administration and other fees. Additionally, the amount you pay may vary by healthcare provider as well. Terms and conditions apply.

My healthcare provider ordered VYEPTI through a specialty pharmacy. What does that mean, and what will I have to do? 

If VYEPTI was ordered through a specialty pharmacy, you will need to complete these few steps to ensure that your prescription is filled and shipped to your selected infusion location.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.