What is VYEPTI?   

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults. It is the first and only FDA-approved intravenous (IV) infusion treatment that’s proven to reduce monthly migraine days. VYEPTI is given by a healthcare provider as a 30-minute IV infusion 4 times a year (every 3 months).

What are the benefits of treatment with VYEPTI?  

VYEPTI is a powerful preventive treatment for migraine that’s proven to reduce monthly migraine days from the very first treatment. More people treated with VYEPTI had fewer monthly migraine days through month 3 compared with placebo.

When will I know if VYEPTI is working?

Everyone is different. When VYEPTI starts working will vary from person to person. Some people have had fewer migraine days the first week after treatment, even as soon as the next day.* Keep track of your monthly migraine days and discuss them with your healthcare provider. 

*After the first infusion, compared with placebo, as described in the FDA-approved prescribing information.

What are the most common side effects of VYEPTI?

The most common side effects of VYEPTI include stuffy nose, scratchy throat, and allergic reactions. These are not all the side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Please see Important Safety Information below and read the VYEPTI Patient Information to see all of the possible side effects.

Could VYEPTI be right for me?  

Talk with your healthcare provider to find out if treatment with VYEPTI may be right for you. If migraine is holding you back, preventive migraine treatment with VYEPTI could help. Here are 2 ways to help start the conversation:

• Take the interactive Living With Migraine Quiz to see how migraine affects your daily life
• Customize the Doctor Discussion Guide and choose questions that are most important to you. Bring the guide to your next appointment and talk to your healthcare provider about VYEPTI    
   

What is the difference between an IV infusion and an injection?

While they are both ways to deliver medicine, they put it in different places of the body. An infusion delivers the medicine directly into the bloodstream. Some injections release the medication into the muscle, while others are injected under the skin.

VYEPTI is an IV infusion for the preventive treatment of migraine. Each VYEPTI infusion is given every 3 months. 100% of the medication is delivered directly into your bloodstream so it can start working fast.

What if I have a migraine attack on the day of my VYEPTI infusion?

Some people in the VYEPTI clinical studies had migraine on the day they received treatment. While there are no limitations of use with VYEPTI, if you have a migraine on the day of your scheduled VYEPTI infusion, talk with your healthcare provider.

What do I need to do to prepare for my 30-minute VYEPTI treatment?

There are a few things you can do to help you feel more comfortable with your VYEPTI treatment, including:

Before: Drink plenty of water, confirm where you're going to get your infusion, and enroll in VYEPTI GO for more helpful information to help you prepare for the infusion.

During: Relax and ask any questions you may have.

After: Make your next infusion appointment in 3 months and get back to your daily routine.

Can VYEPTI be given to people who are pregnant or planning to become pregnant?

Before a person is given VYEPTI, they should tell their healthcare provider if they are pregnant or plan to become pregnant, or if they are breastfeeding or planning to breastfeed. Read the VYEPTI Important Safety Information.

Can my primary care provider prescribe VYEPTI, or will I need to be referred to a specialist? 

Although VYEPTI can be prescribed by any authorized healthcare provider, they may refer you to a migraine/headache specialist or a neurologist. 

Is there a patient support program for VYEPTI?

There are 3 support programs for people thinking about starting or who have started VYEPTI.

If you’re looking into details of your healthcare insurance coverage or need help finding treatment locations, VYEPTI CONNECT can provide you with informational support as you start your treatment journey. Through VYEPTI GO, you can speak with a registered nurse for personalized support. Learn more about how VYEPTI CONNECT and VYEPTI GO can help.

Interested in talking 1-on-1 with someone who can tell you about their personal migraine experiences, including taking VYEPTI? Connect with a mentor through the MVP Mentor Program.

Is there a way to save on the cost of VYEPTI?

The VYEPTI CONNECT Copay Assistance Program helps eligible people with commercial insurance pay as little as $0 every 3 months for VYEPTI. Interested in enrolling? Check your eligibility.

Offer includes up to $200 in administration fees per VYEPTI treatment. Additionally, the amount you pay may vary by healthcare provider as well. A maximum annual limit and Terms and Conditions apply.

My healthcare provider ordered VYEPTI through a specialty pharmacy. What does that mean, and what will I have to do? 

If VYEPTI was ordered through a specialty pharmacy, you will need to complete these few steps to ensure that your prescription is filled and shipped to your selected infusion location.

What is migraine?

Migraine is more than just a bad headache; it’s a neurological disease that affects over 39 million Americans. It’s likely that you or someone you know suffers from migraine.

Symptoms can be different for everyone. Some people may have throbbing head pain, be sensitive to light and sound, feel sick to their stomach, and/or vomit.

The number of migraine attacks each month can vary. Some people have 15 or more migraine days a month. This can really impact your quality of life—more than 90% of people are unable to work or live their lives normally during their migraine.