Female patient helping her son put on his jacket.

VYEPTI in Real Life

Living with VYEPTI

Actor portrayal

Proven to reduce monthly migraine days

In VYEPTI clinical trials:

  • People with chronic migraine had an average of 8 fewer migraine days a month with VYEPTI over 3 months vs 6 with placebo
  • People with episodic migraine had an average of 4 fewer migraine days a month with VYEPTI over 3 months vs 3 with placebo

The most common side effects of VYEPTI in the clinical trials were stuffy nose and scratchy throat, and allergic reactions.

 

Clinical trials vs real-world data

Clinical trials are the way researchers learn how well VYEPTI works in a controlled setting. After clinical trials, researchers continue learning from people using VYEPTI in everyday life.

This real-world data often comes from things like surveys or medical records. It’s not as strict as a clinical trial, so this information is not proof that VYEPTI works. But it can help support the results of the clinical trials and gives a helpful look at how VYEPTI is being used by real people, in real life.

The information below comes from this kind of real-world data.

Because of the way these data were collected, we cannot make any conclusions about how well VYEPTI works based on these results.

In a survey of people with chronic migraine, here's what people said they experienced on VYEPTI

Survey goal

Understand people's satisfaction with VYEPTI in the real world outside of a clinical trial.

People who took the survey

94 people diagnosed with chronic migraine. 52% of people were receiving VYEPTI for a year or more. All patients tried other preventive treatments for migraine before receiving VYEPTI and could be on other medications.

Survey responses

Based on patients' memories of their experiences before starting VYEPTI. Relying on memory of past events may enhance the results, and your experience may be different than described.

""

80% said they were satisfied with VYEPTI's ability to reduce symptom severity

Answers ranged from strongly disagree/disagree to strongly agree/agree. A person was counted as "satisfied" if they answered they strongly agree or agree with each statement about being satisfied with VYEPTI's abilities.

""

76% said they were satisfied with VYEPTI's ability to reduce symptom frequency

Answers ranged from strongly disagree/disagree to strongly agree/agree. A person was counted as "satisfied" if they answered they strongly agree or agree with each statement about being satisfied with VYEPTI's abilities.

""

86% reported improvement in brain fog

74 of the 94 study patients said they had experienced brain fog (feeling confused, having difficulty learning/remembering, or having trouble speaking/reading) and were asked to rate the level of improvement, if any, during the treatment period. Results shown include slight, moderate, or significant improvement. There was no opportunity in this study for patients to report new or worsened brain fog while on VYEPTI; therefore, the results shown may overrepresent actual improvement during treatment.

Images above feature real VYEPTI patients who were compensated for their time. These patients did not participate in the survey.

""

“Having more migraine-free days with VYEPTI has made a big difference in my life. I'm able to go to baseball games, concerts, enjoy my family, and little things like reading.”


Florian, VYEPTI patient

Individual results may vary.
Florian was compensated for his time.

VYEPTI® patient ambassador Florian smiling.

Swipe for more

Be informed

Understanding VYEPTI

side effects

Here's what side effects people receiving VYEPTI experienced in clinical studies.

How to start the conversation

Ask your doctor if VYEPTI could be a yep for you

Before your next appointment, create your own Doctor Discussion Guide with personalized responses specific to your concerns and experience with migraine.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

VYEPTI may cause serious side effects such as:

  • Allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.
  • High blood pressure. High blood pressure or worsening of high blood pressure can happen after receiving VYEPTI. Contact your healthcare provider if you have an increase in blood pressure.
  • Raynaud’s phenomenon. A type of circulation problem (Raynaud’s phenomenon) can worsen or happen after receiving VYEPTI. Contact your healthcare provider if you have symptoms such as your fingers or toes feeling numb, cool, or painful, or changing color from pale to blue to red.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you have high blood pressure; circulation problems in your fingers and toes; are pregnant or plan to become pregnant; or are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions. These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

IMPORTANT SAFETY INFORMATION

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

VYEPTI may cause serious side effects such as:

  • Allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.
  • High blood pressure. High blood pressure or worsening of high blood pressure can happen after receiving VYEPTI. Contact your healthcare provider if you have an increase in blood pressure.
  • Raynaud’s phenomenon. A type of circulation problem (Raynaud’s phenomenon) can worsen or happen after receiving VYEPTI. Contact your healthcare provider if you have symptoms such as your fingers or toes feeling numb, cool, or painful, or changing color from pale to blue to red.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you have high blood pressure; circulation problems in your fingers and toes; are pregnant or plan to become pregnant; or are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions. These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.