The power of VYEPTI migraine prevention

Proven to reduce monthly migraine days with the very first treatment

It’s possible to be migraine-free on day 1 icon

With VYEPTI, more people had migraine-free days during the first week after treatment, some as soon as Day 1.*

*After the first infusion, compared with placebo, as described in the FDA-approved prescribing information.

8 fewer migraine days a month icon

People treated with VYEPTI had 8 fewer migraine days a month on average compared to 6 with placebo.

Just 30 minutes 4x a year icon

Just one 30-minute treatment 4x a year (every 3 months).

*After the first infusion, compared with placebo, as described in the FDA-approved prescribing information.

It’s time for fast, powerful, and lasting prevention with VYEPTI

In a study of adults with chronic migraine who averaged 16 migraine days a month, lasting reduction in monthly migraine days was seen through Month 3 after a single treatment of VYEPTI 100 mg. 

VYEPTI 100 mg is the recommended dose, but your healthcare provider may decide that you could benefit from a 300 mg dose.

†15 or more headache days per month with at least 8 of those being migraine days.

In a study of adults with episodic migraine who averaged 9 migraine days a month, people treated with VYEPTI had 4 fewer migraine days a month on average compared to 3 with placebo. Lasting reduction in monthly migraine days was seen through month 3 after a single treatment of VYEPTI 100 mg.

‡4-14 headache days per month with at least 4 of those being migraine days.

Treatment that’s well tolerated

In 2 clinical studies of more than 1700 people with migraine, the most common side effects were:

  • Stuffy nose and scratchy throat (6-8%)
  • Allergic reactions (0-2%)

Most common side effects were reported by at least 2% of people receiving VYEPTI and at least 2% more common than those on placebo.

Tell your healthcare provider if you become pregnant or plan to become pregnant.

1.9% of people stopped VYEPTI because of side effects

How VYEPTI is given

VYEPTI is given as an intravenous (IV) infusion by a healthcare provider. Here are some tips on what you can expect before, during, and after your VYEPTI infusion.

Tips for your VYEPTI infusion

Click on Before, During, and After below to see what you may expect with treatment.

Hydrate icon
Get ready for your infusion
  • Drink plenty of water leading up to your appointment so that you are well hydrated
  • Wear comfortable clothing. Make sure long sleeves can be rolled up over your elbow
  • Bring an extra layer in case the infusion location is chilly
VYEPTI Locator icon
Have what you need and know where you’re going
  • As with most appointments with a healthcare provider, bring needed paperwork with you, such as a list of all medications you are taking
  • Have the address of the infusion location handy, as it may be different from where you go to see your healthcare provider
VYEPTI GO logo
Get personalized support

Enroll in VYEPTI GO to receive helpful information, resources, and tips to get you started.

Healthcare provider icon
Given by a healthcare provider
  • A nurse or other healthcare provider will start your infusion and be available to answer any questions you may have.
  • VYEPTI 100 mg is the recommended dose, but your healthcare provider may decide that you could benefit from a 300 mg dose.
30-minute infusion time icon
Infusion time

The infusion will take about 30 minutes, but your total appointment time may vary.

Phone and book icon
Sit back and relax

Use this time to read, use your phone to check emails, connect with others on social media, or just relax.

VYEPTI calendar icon
Make your next appointment

Schedule your next VYEPTI appointment in 3 months before you leave the infusion location.

Daily activities icon
Return to your daily activities

Once your infusion is over, you can go about your day.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

icon quotemarks tint 64px

“Before my first infusion, I was a little bit nervous. But for me, it was easy and the 30 minutes went by really quickly.”

Lealani, real VYEPTI patient

Given by a healthcare provider as a 30-minute IV, 4x per year. Individual results may vary.

Image of a man with child in stroller

What could you do with more migraine-free days?

Start the discussion with your healthcare provider to see if VYEPTI could be right for you.

VYEPTI is designed to start working fast and to last

Science Animation

VYEPTI is given as a 30-minute IV infusion 4x a year.

Water Person Animation

of the medication is delivered into your bloodstream.

The science of VYEPTI

CGRP in body icon

Inside the body, there is a protein called calcitonin gene-related peptide, or CGRP.

CGRP and receptors icon

CGRP attaches to and activates specific receptors, which may play a role in migraine.

Medication in bloodstream icon

VYEPTI binds to CGRP and prevents it from attaching to and activating the receptors.

The relationship between your body’s response to the medication and how VYEPTI prevents migraine is not known.

VYEPTI GO logo

Ready to start VYEPTI?

There's a program you can enroll in called VYEPTI GO that offers personalized support, resources, and more.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.

APPROVED USE

VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.

IMPORTANT SAFETY INFORMATION
AND APPROVED USE

Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.

VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing; hives; or redness in your face.

Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.

These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the Prescribing Information and Patient Information.