ABOUT VYEPTI (eptinezumab-jjmr)
How does VYEPTI work?
VYEPTI works by blocking calcitonin gene-related peptide, or CGRP, a substance in your brain that is thought to play a role in triggering migraine.
Why is VYEPTI given as an IV treatment?
VYEPTI was designed to be given as an intravenous (IV) treatment so 100% of the medication would be available in the bloodstream to quickly start working.
Is there anyone who should not receive VYEPTI?
Do not receive VYEPTI if you are allergic to eptinezumab-jjmr or its ingredients. View the patient information for a complete list of ingredients.
How long does VYEPTI work?
VYEPTI is given by IV every 3 months. Studies show that people taking VYEPTI continued to have fewer migraine days throughout the duration of the study.
What are the most common side effects of VYEPTI?
The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions. These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
Should I stop my current migraine treatment before starting VYEPTI?
Always talk to your doctor before stopping any medication.
Can I take VYEPTI if I am pregnant or planning to become pregnant?
Before you use VYEPTI, tell your doctor if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.
Is there someone to call if I have questions or concerns about VYEPTI?
Talk to your doctor if you have questions or concerns about VYEPTI treatment. You are encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Is VYEPTI available only from a specialist, or can I get VYEPTI from my doctor?
VYEPTI is a medication that can be prescribed by any licensed physician, although your family doctor may refer you to a neurologist or headache specialist for migraine treatment.
VYEPTI (eptinezumab-jjmr) IV TREATMENT
What do I need to do to prepare for my IV treatment?
Drink plenty of water, get a good night’s sleep, and bring a list of any medications and supplements you take. Unless told otherwise, you don’t have to fast before your VYEPTI IV migraine treatment.
How long will my VYEPTI treatment take?
VYEPTI is given as a 30-minute IV treatment every 3 months, but the amount of time spent for preparation beforehand and monitoring may vary.
Talk to your doctor about what to expect before, during, and after treatment. Always report any side effects you may experience.
What should I expect on the day of treatment?
Each IV treatment will begin with a quick checkup of your vital signs, including your temperature. The IV infusion itself is given as a 30-minute treatment.
Should you experience any side effects, be sure to tell your healthcare team.
Do my appointments have to be exactly 12 weeks apart?
For best results, VYEPTI should be given every 12 weeks for migraine prevention. Your doctor or nurse will schedule your appointment for you. Make sure to schedule your next infusion appointment before you leave the clinic.
What should I do if I have a migraine on the day of my treatment?
If you have a migraine the day of your IV treatment, talk to your healthcare provider.
What should I wear to my VYEPTI IV treatment?
Some clinics can be chilly, so dress appropriately. If you wear a long-sleeved shirt or sweater, make sure the sleeves are loose enough to roll up above your elbows.
What should I bring to my VYEPTI IV treatment?
Bring a list of any medications or supplements you take, including the doses and how often you take them. You may also want to bring a book, magazine, or electronic device to keep busy during your 30-minute infusion and any waiting time.
SUPPORT WITH COMMERCIAL COPAY ASSISTANCE
What is commercial copay assistance?
Through the VYEPTI Copay Assistance Program, eligible commercial patients can get a portion of the cost of treatment paid for by Lundbeck. Terms and conditions apply.
How do I find out if I qualify for the commercial copay assistance?
Please go to the VYEPTI Copay Assistance Program page or call 1-833-4-VYEPTI (1-833-489-3784) to find out if you’re eligible. Terms and conditions apply.
LIVING WITH MIGRAINE AND MIGRAINE PREVENTION TREATMENT
How common is migraine?
Migraine impacts about 39 million Americans.
What is migraine prevention treatment?
Migraine preventive medications are meant to reduce the number of your migraine attacks and stop new attacks before they even start.
Sometimes I can’t work or participate in daily activities when I have a migraine attack. Does this happen to other people?
Yes. More than 90% of people with migraine aren’t able to work or function normally during migraine attacks.
Where can I connect with other people who have migraine?
A number of resources are available to connect you to the migraine community. Visit this page to see a few online forums
References:
- VYEPTI [package insert]. Deerfield, IL: Lundbeck Seattle BioPharmaceuticals, Inc.
- Ho TW, Edvinsson L, Goadsby PJ. CGRP and its receptors provide new insights into migraine pathophysiology. Nat Rev Neurol. 2010;6(10):573-582.
- Dodick DW, Lipton RB, Silberstein S, et al. Eptinezumab for prevention of chronic migraine: a randomized phase 2b clinical trial. Cephalalgia. 2019;39(9):1075-1085.
- Miller S. The acute and preventative treatment of episodic migraine. Ann Indian Acad Neurol. 2012;15(suppl 1):S33-S39.
- How to prepare for your infusion. National Infusion Center Association. Accessed October 17, 2019.
https://infusioncenter.org/how-to-prepare-for-your-infusion/. - Migraine facts. Migraine Research Foundation. Accessed March 27, 2020.
https://migraineresearchfoundation.org/about-migraine/migraine-facts/.
IMPORTANT SAFETY INFORMATION
AND APPROVED USE
Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.
APPROVED USE
VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.
VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash, swelling of your face, lips, tongue, or throat, if you have trouble breathing, hives or redness in your face.
Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.
Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.
The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.
These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For more information, please see the Prescribing Information and Patient Information.
APPROVED USE
VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults.
IMPORTANT SAFETY INFORMATION
AND APPROVED USE
Do not receive VYEPTI if you have a known allergy to eptinezumab-jjmr or its ingredients.
VYEPTI may cause allergic reactions. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash, swelling of your face, lips, tongue, or throat, if you have trouble breathing, hives or redness in your face.
Before starting VYEPTI, tell your healthcare provider about all your medical conditions, including if you are pregnant or plan to become pregnant, or you are breastfeeding or plan to breastfeed.
Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.
The most common side effects of VYEPTI include stuffy nose and scratchy throat, and allergic reactions.
These are not all the possible side effects of VYEPTI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For more information, please see the Prescribing Information and Patient Information.
© 2020 Lundbeck. All rights reserved. VYEPTI and VYEPTI GO are trademarks of Lundbeck Seattle BioPharmaceuticals, Inc. EPT-B-100034
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